The tourists went to the close on 213 for one in their second innings, but still trail South Africa by 208 runs after they were forced to follow-on having been bowled out for 194 earlier in the day.
Ryan Rickelton posted the joint seventh-highest score by a South African in Tests with 259 as his side ran up a huge 615 before reducing Pakistan to 64/4 at the close on Day 2.
Ryan Rickelton struck a career-best unbeaten 176 and his captain Temba Bavuma scored 106 as South Africa pummelled Pakistan's seamers at Newlands to finish the first day of the second and final Test on 316 for four on Friday.
South Africa are within touching distance of a place in next June's World Test Championship final at Lord's but must win at least one of their two Tests against Pakistan
Pakistan completed a clean sweep of their One-day International series in South Africa with victory by 36 runs in the third and final clash at The Wanderers on Sunday.
Pakistan were always struggling to keep up the required run rate despite captain Mohamed Rizwan batting through to the last over before being dismissed for 74.
South Africa's two-test series success over Sri Lanka on Monday catapulted them to first place in the World Test Championship and put them firmly on course for next year's final in what would have been unthinkable less than a year ago.
Heinrich Klaasen will captain South Africa in three Twenty20 matches against Pakistan next week.
'I don't know what the maths looks like but we're playing good cricket and we want it to continue.'
The third Twenty20 International between South Africa and India was halted early in the home side's reply after a wave of flying ants descended on Centurion Park in Pretoria on Wednesday and forced the players from the field.
Top bowler Kagiso Rabada will be rested for the series, along with Lungi Ngidi, as South Africa look ahead to the two-Test series against Sri Lanka, which begins later in November.
Ganguly joined Delhi Capitals in 2019 as an advisor, where he worked alongside coach Ricky Ponting, and later returned to the franchise as Director of Cricket after his stint as BCCI president.
Hampshire became the first county championship club to be owned by an overseas franchise.
South African former high jump World champion Jacques Freitag has been found dead with gunshot wounds having been missing for two weeks, South African media reported on Tuesday.
Eight of South Africa's top cricket stadiums, including Wanderers in Johannesburg, Durban's Kingsmead and Newlands in Cape Town, have been confirmed as venues for the 2027 ICC ODI World Cup, a News24 report said on Wednesday.
New Zealand's former star batter Ross Taylor has suggested that fast bowler Neil Wagner's retirement was "forced", hinting at the possibility of unrest in the Kiwi camp.
New Zealand paceman Neil Wagner called time on his 64-Test career on Tuesday, bowing out as the nation's fifth highest wicket-taker with 260 victims after being informed he would not be selected in the upcoming series against Australia.
Sunrisers Eastern Cape completed back-to-back title success in the SA20 with a thumping 89-run victory over Durban Super Giants
Israeli Prime Minister Benjamin Netanyahu marked 100 days of Israel's war against Hamas in the Gaza Strip on Saturday night by reiterating his vow to continue fighting until the Palestinian terror group is defeated.
The Uday Saharan-led Indian colts shared the top honours with their South African counterparts in the Tri-Nation Under-19 Tournament after the title clash was called off due to rain in Johannesburg on Wednesday.
Injury to Temba Bavuma also thrust Elgar back into the captain's role that was taken away from him last February.
South Africa is one of the most challenging places in the world for batters and the side which can adapt to the seamer friendly conditions quickest has the best chance of success in the first Test against India, according to home captain Temba Bavuma.
South African athlete Oscar Pistorius, known as the "Blade Runner" for his carbon-fibre prosthetic legs, was released on parole on Friday, nearly 11 years after murdering his girlfriend.
South Africa are hopeful that both fast bowlers Kagiso Rabada and Lungi Ngidi will be available for selection in the first Test against India that gets underway in Pretoria on Tuesday, coach Shukri Conrad has confirmed.
23 wickets and several records fell on the opening day of the second and final Test in Cape Town on Wednesday.
What will happen to Oscar Pistorius when he is released from jail?
Former Sri Lanka cricketer and current Rajasthan Royals coach and Director of Cricket Kumar Sangakkara expressed happiness on wicketkeeper-batter Dhruv Jurel earning the India call-up for the Test series against England at home, saying that the player understands pressure well and has a fine work ethic.
Shubman Gill was at his silken best during Indian team's intra-squad training game here at the Tuks Oval on Thursday even though there wasn't an opportunity to get a glimpse of that enchanting sight.
De Zorzi ton guides South Africa to eight-wicket win over India
Arshdeep Singh and Avesh Khan helped skittle South Africa out for 116 before Sai Sudharsan scored an unbeaten 55 on debut as India romped to an eight-wicket victory.
Virat Kohli came into the Centurion Test with only one proper net session on Christmas eve but India batting coach Vikram Rathour categorical said that at this stage of his career, the former captain doesn't need to train a lot.
South African former Paralympic star Oscar Pistorius is set to be released on parole on Friday, nearly 11 years after murdering his girlfriend Reeva Steenkamp in a crime that shocked a nation long inured to violence against women.
'As long as the guys understand the way that we want to try play as a team and can keep that close to them when playing in different leagues and tournaments. Then hopefully by the time we meet up for the World Cup, the guys are used to that brand and how we want to operate as a team.'
South Africa's Lungi Ngidi ruled out of India T20 series
World No 1 India may feel they have never had a better chance of winning their first ever Test series in South Africa.
A spokesperson for South Africa's Department of Correctional Services said a parole board would consider Pistorius's case at a hearing on Friday, where they will decide if he should be released on parole.
South Africa have rested batter Temba Bavuma for their home white-ball series against India this month after a poor Cricket World Cup, but he will captain the team in the two-Test series which starts on Dec. 26.
'There will be an extended period of time out and we're just going to weigh whether that time falls potentially with an option to carry him through the front half of the World Cup.'
Australian opener Travis Head's participation at next month's World Cup is in doubt after he broke his hand during Friday's one day international against South Africa.
'The 50-over format is very hard on the body but that's something I wanted to experience. I always like to challenge myself.'